Cargando…
Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK
BACKGROUND: Andrographolide is the major labdane diterpenoid originally isolated from Andrographis paniculata and has been shown to have anti-inflammatory and antioxidative effects. However, there is a dearth of studies on the potential therapeutic utility of andrographolide in neuroinflammatory con...
Autores principales: | Wong, Siew Ying, Tan, Michelle G. K., Wong, Peter T. H., Herr, Deron R., Lai, Mitchell K. P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034653/ https://www.ncbi.nlm.nih.gov/pubmed/27663973 http://dx.doi.org/10.1186/s12974-016-0723-3 |
Ejemplares similares
-
Andrographolide attenuates LPS-stimulated up-regulation of C-C and C-X-C motif chemokines in rodent cortex and primary astrocytes
por: Wong, Siew Ying, et al.
Publicado: (2016) -
Morin Induces Heme Oxygenase-1 via ERK-Nrf2 Signaling Pathway
por: Park, Ji Young, et al.
Publicado: (2013) -
Isoegomaketone Upregulates Heme Oxygenase-1 in RAW264.7 Cells via ROS/p38 MAPK/Nrf2 Pathway
por: Jin, Chang Hyun, et al.
Publicado: (2016) -
Heme Oxygenase-1 Regulates Dendritic Cell Function through Modulation of p38 MAPK-CREB/ATF1 Signaling
por: Al-Huseini, Laith M. A., et al.
Publicado: (2014) -
Hemin inhibits NO production by IL-1β-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation
por: Sheng, Wen S, et al.
Publicado: (2010)