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The emerging role of lysine methyltransferase SETD8 in human diseases

SETD8/SET8/Pr-SET7/KMT5A is the only known lysine methyltransferase (KMT) that monomethylates lysine 20 of histone H4 (H4K20) in vivo. Lysine residues of non-histone proteins including proliferating cell nuclear antigen (PCNA) and p53 are also monomethylated. As a consequence, the methyltransferase...

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Detalles Bibliográficos
Autores principales:	Milite, Ciro, Feoli, Alessandra, Viviano, Monica, Rescigno, Donatella, Cianciulli, Agostino, Balzano, Amodio Luca, Mai, Antonello, Castellano, Sabrina, Sbardella, Gianluca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034662/ https://www.ncbi.nlm.nih.gov/pubmed/27688818 http://dx.doi.org/10.1186/s13148-016-0268-4

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