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Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight
OBJECTIVE: We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and may improve insulin sensitivity in high-fat fed mice. We hypothesized that knocking out the adipose tissue (P)RR gene would prevent weight gain and in...
Autores principales: | Shamansurova, Zulaykho, Tan, Paul, Ahmed, Basma, Pepin, Emilie, Seda, Ondrej, Lavoie, Julie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034688/ https://www.ncbi.nlm.nih.gov/pubmed/27689008 http://dx.doi.org/10.1016/j.molmet.2016.08.009 |
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