Multi‐omic profiling ­of EPO‐producing Chinese hamster ovary cell panel reveals metabolic adaptation to heterologous protein production

Chinese hamster ovary (CHO) cells are the preferred production host for many therapeutic proteins. The production of heterologous proteins in CHO cells imposes a burden on the host cell metabolism and impact cellular physiology on a global scale. In this work, a multi‐omics approach was applied to s...

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Detalles Bibliográficos
Autores principales: Ley, Daniel, Seresht, Ali Kazemi, Engmark, Mikael, Magdenoska, Olivera, Nielsen, Kristian Fog, Kildegaard, Helene Faustrup, Andersen, Mikael Rørdam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034845/
https://www.ncbi.nlm.nih.gov/pubmed/25995028
http://dx.doi.org/10.1002/bit.25652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034845/
https://www.ncbi.nlm.nih.gov/pubmed/25995028
http://dx.doi.org/10.1002/bit.25652

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