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Genomic Analysis Reveals a Common Breakpoint in Amplifications of the Plasmodium vivax Multidrug Resistance 1 Locus in Thailand

In regions of coendemicity for Plasmodium falciparum and Plasmodium vivax where mefloquine is used to treat P. falciparum infection, drug pressure mediated by increased copy numbers of the multidrug resistance 1 gene (pvmdr1) may select for mefloquine-resistant P. vivax. Surveillance is not undertak...

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Detalles Bibliográficos
Autores principales:	Auburn, Sarah, Serre, David, Pearson, Richard D., Amato, Roberto, Sriprawat, Kanlaya, To, Sheren, Handayuni, Irene, Suwanarusk, Rossarin, Russell, Bruce, Drury, Eleanor, Stalker, Jim, Miotto, Olivo, Kwiatkowski, Dominic P., Nosten, Francois, Price, Ric N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034950/ https://www.ncbi.nlm.nih.gov/pubmed/27456706 http://dx.doi.org/10.1093/infdis/jiw323

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