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Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor

19(S)-hydroxy-eicosatetraenoic acid (19(S)-HETE) belongs to a family of arachidonic acid metabolites produced by cytochrome P450 enzymes, which play critical roles in the regulation of cardiovascular, renal and pulmonary functions. Although it has been known for a long time that 19(S)-HETE has vascu...

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Detalles Bibliográficos
Autores principales: Tunaru, Sorin, Chennupati, Ramesh, Nüsing, Rolf M., Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035018/
https://www.ncbi.nlm.nih.gov/pubmed/27662627
http://dx.doi.org/10.1371/journal.pone.0163633