Cargando…

Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek’s Disease Virus

Marek’s disease (MD), caused by Marek’s disease virus (MDV), a poultry-borne alphaherpesvirus, is a devastating disease of poultry causing an estimated annual loss of one billion dollars to poultry producers, worldwide. Despite decades of control through vaccination, MDV field strains continue to em...

Descripción completa

Detalles Bibliográficos
Autores principales:	Padhi, Abinash, Parcells, Mark S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035050/ https://www.ncbi.nlm.nih.gov/pubmed/27662574 http://dx.doi.org/10.1371/journal.pone.0162180

Ejemplares similares

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence
por: Sato, Jumpei, et al.
Publicado: (2022)

Sequence analysis of Meq oncogene among Indian isolates of Marek's disease herpesvirus
por: Gupta, Mridula, et al.
Publicado: (2016)

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus
por: Sun, Peng, et al.
Publicado: (2020)

Research Note: Characterization of S-Meq containing the deletion in Meq protein's transactivation domain in a Marek's disease virus strain in Japan
por: Murata, Shiro, et al.
Publicado: (2021)

Newly detected mutations in the Meq oncogene and molecular pathotyping of very virulent Marek’s disease herpesvirus in Tunisia
por: Lachheb, Jihene, et al.
Publicado: (2020)

Diversity of Meq gene from clinical Marek’s disease virus infection in Saudi Arabia
por: Mohamed, Mahmoud H. A., et al.
Publicado: (2016)

Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek's disease virus
por: Li, Yanpeng, et al.
Publicado: (2011)

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities
por: Deng, Xufang, et al.
Publicado: (2010)

Marek’s disease virus oncoprotein Meq physically interacts with the chicken infectious anemia virus-encoded apoptotic protein apoptin
por: Brown, Andrew C., et al.
Publicado: (2018)

Transcriptional Profiling of MEq-Dependent Genes in Marek’s Disease Resistant and Susceptible Inbred Chicken Lines
por: Subramaniam, Sugalesini, et al.
Publicado: (2013)

A Special Issue on Marek’s Disease Virus—The Editors’ View
por: Kaufer, Benedikt B., et al.
Publicado: (2023)

Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective
por: Conrad, Steven J., et al.
Publicado: (2021)

Marek’s disease virus Meq oncoprotein interacts with chicken HDAC 1 and 2 and mediates their degradation via proteasome dependent pathway
por: Liao, Yifei, et al.
Publicado: (2021)

A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021
por: Song, Baolin, et al.
Publicado: (2022)

Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses
por: Teng, Man, et al.
Publicado: (2023)

Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection
por: Sun, Aijun, et al.
Publicado: (2022)

Comparison of the Transcriptomes and Proteomes of Serum Exosomes from Marek’s Disease Virus-Vaccinated and Protected and Lymphoma-Bearing Chickens
por: Neerukonda, Sabari Nath, et al.
Publicado: (2019)

Positive natural selection in the evolution of human metapneumovirus attachment glycoprotein
por: Padhi, Abinash, et al.
Publicado: (2008)

Marek’s Disease Virus Activates the PI3K/Akt Pathway Through Interaction of Its Protein Meq With the P85 Subunit of PI3K to Promote Viral Replication
por: Li, Huimin, et al.
Publicado: (2018)

Genetic evolution of Marek’s disease virus in vaccinated poultry farms
por: Yehia, Nahed, et al.
Publicado: (2021)

Out of Sight, but Not Out of Mind: Aspects of the Avian Oncogenic Herpesvirus, Marek’s Disease Virus
por: Davidson, Irit
Publicado: (2020)

A comparison of exosome purification methods using serum of Marek's disease virus (MDV)-vaccinated and -tumor-bearing chickens
por: Neerukonda, Sabari Nath, et al.
Publicado: (2020)

Revisiting cellular immune response to oncogenic Marek’s disease virus: the rising of avian T-cell immunity
por: Yang, Yi, et al.
Publicado: (2020)

Chuwi meq'en ja' = Comunidad y liderazgo en la Guatemala K'iche'
por: Ekern, Stener
Publicado: (2010)

Marek’s disease virus and skin interactions
por: Couteaudier, Mathilde, et al.
Publicado: (2014)

The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus
por: Warren, Wesley C., et al.
Publicado: (2023)

Co-Infection with Marek’s Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek’s Disease Vaccine Efficacy
por: Sun, Guo-Rong, et al.
Publicado: (2017)

Deletion of 1.8-kb mRNA of Marek's disease virus decreases its replication ability but not oncogenicity
por: Sun, Aijun, et al.
Publicado: (2010)

Data on meq gene sequence analysis of Ludhiana MDV isolates
por: Gupta, Mridula, et al.
Publicado: (2016)

The prognostic validity of the formative for the summative MEQ (Modified Essay Questions)
por: Büssing, Oliver, et al.
Publicado: (2021)

Mapping QTL Associated with Resistance to Avian Oncogenic Marek’s Disease Virus (MDV) Reveals Major Candidate Genes and Variants
por: Smith, Jacqueline, et al.
Publicado: (2020)

Modeling Marek’s disease virus transmission: A framework for evaluating the impact of farming practices and evolution
por: Kennedy, David A., et al.
Publicado: (2018)

Latest Insights into Marek’s Disease Virus Pathogenesis and Tumorigenesis
por: Bertzbach, Luca D., et al.
Publicado: (2020)

Marek’s Disease Virus Infection of Natural Killer Cells
por: Bertzbach, Luca D., et al.
Publicado: (2019)

Recombinant Marek’s disease virus type 1 provides full protection against very virulent Marek’s and infectious bursal disease viruses in chickens
por: Li, Kai, et al.
Publicado: (2016)

Comparative analysis of oncogenic genes revealed unique evolutionary features of field Marek's disease virus prevalent in recent years in China
por: Tian, Mingxing, et al.
Publicado: (2011)

Marek’s Disease Virus Infection Induced Mitochondria Changes in Chickens
por: Chu, Qin, et al.
Publicado: (2019)

Molecular epidemiology of Marek’s disease virus in central Pennsylvania, USA
por: Bell, Andrew S, et al.
Publicado: (2019)

Antiviral effect of baicalin on Marek’s disease virus in CEF cells
por: Yang, Fan, et al.
Publicado: (2020)

Glutaminolysis and Glycolysis Are Essential for Optimal Replication of Marek’s Disease Virus
por: Boodhoo, Nitish, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7f3enmtsohdr9e7kc75dhfu7r2