Procainamide Inhibits DNA Methylation and Alleviates Multiple Organ Dysfunction in Rats with Endotoxic Shock

Excessive inflammatory and oxidative stress lead to circulatory failure, multiple organ dysfunction, and high mortality in patients with sepsis. Microbial infection-induced DNA hypermethylation is associated with the augmentation of inflammation and oxidative stress. In our previous study, the antia...

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Detalles Bibliográficos
Autores principales: Shih, Chih-Chin, Liao, Mei-Hui, Hsiao, Tsan-Seng, Hii, Hiong-Ping, Shen, Ching-Hui, Chen, Shiu-Jen, Ka, Shuk-Man, Chang, Yung-Lung, Wu, Chin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035080/
https://www.ncbi.nlm.nih.gov/pubmed/27661616
http://dx.doi.org/10.1371/journal.pone.0163690

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