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GABA deficiency in NF1: A multimodal [(11)C]-flumazenil and spectroscopy study

OBJECTIVE: To provide a comprehensive investigation of the γ-aminobutyric acid (GABA) system in patients with neurofibromatosis type 1 (NF1) that allows understanding the nature of the GABA imbalance in humans at pre- and postsynaptic levels. METHODS: In this cross-sectional study, we employed multi...

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Detalles Bibliográficos
Autores principales: Violante, Inês R., Patricio, Miguel, Bernardino, Inês, Rebola, José, Abrunhosa, Antero J., Ferreira, Nuno, Castelo-Branco, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035153/
https://www.ncbi.nlm.nih.gov/pubmed/27473134
http://dx.doi.org/10.1212/WNL.0000000000003044

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