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Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

This article contains data related to the research article entitled “Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance” by Bildsoe et al. (2016) [1]. The data presented here are derived from: (1) a microarray-based comparison of so...

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Detalles Bibliográficos
Autores principales: Bildsoe, Heidi, Fan, Xiaochen, Wilkie, Emilie E., Ashoti, Ator, Jones, Vanessa J., Power, Melinda, Qin, Jing, Wang, Junwen, Tam, Patrick P.L., Loebel, David A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035339/
https://www.ncbi.nlm.nih.gov/pubmed/27699189
http://dx.doi.org/10.1016/j.dib.2016.09.001
Descripción
Sumario:This article contains data related to the research article entitled “Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance” by Bildsoe et al. (2016) [1]. The data presented here are derived from: (1) a microarray-based comparison of sorted cranial mesoderm (CM) and cranial neural crest (CNC) cells from E9.5 mouse embryos; (2) comparisons of transcription profiles of head tissues from mouse embryos with a CM-specific loss-of-function of Twist1 and control mouse embryos collected at E8.5 and E9.5; (3) ChIP-seq using a TWIST1-specific monoclonal antibody with chromatin extracts from TWIST1-expressing MDCK cells, a model for a TWIST1-dependent mesenchymal state.