Data of methylome and transcriptome derived from human dilated cardiomyopathy

Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the ri...

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Detalles Bibliográficos
Autores principales: Jo, Bong-Seok, Koh, In-Uk, Bae, Jae-Bum, Yu, Ho-Yeong, Jeon, Eun-Seok, Lee, Hae-Young, Kim, Jae-Joong, Choi, Murim, Choi, Sun Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035344/
https://www.ncbi.nlm.nih.gov/pubmed/27699191
http://dx.doi.org/10.1016/j.dib.2016.09.006
Descripción
Sumario:Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1].

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