Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I

Leukocyte adhesion deficiency type I (LAD-I) is a primary immunodeficiency caused by mutations in the ITGB2 gene and is characterized by recurrent and life-threatening bacterial infections. These mutations lead to defective or absent expression of β(2) integrins on the leukocyte surface, compromisin...

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Detalles Bibliográficos
Autores principales: Leon-Rico, Diego, Aldea, Montserrat, Sanchez-Baltasar, Raquel, Mesa-Nuñez, Cristina, Record, Julien, Burns, Siobhan O., Santilli, Giorgia, Thrasher, Adrian J., Bueren, Juan A., Almarza, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035374/
https://www.ncbi.nlm.nih.gov/pubmed/27056660
http://dx.doi.org/10.1089/hum.2016.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035374/
https://www.ncbi.nlm.nih.gov/pubmed/27056660
http://dx.doi.org/10.1089/hum.2016.016

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