Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia

BACKGROUND: Osteosarcoma is the most common malignancy of bone. Intratumoral hypoxia occurs in many solid tumors, where it is associated with the development of aggressive phenotype. ANRIL has been shown to be a long noncoding RNA that facilitates the progression of a number of malignancies. Yet, fe...

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Detalles Bibliográficos
Autores principales: Wei, Xiaokang, Wang, Chuanshun, Ma, Chunhui, Sun, Wei, Li, Haoqing, Cai, Zhendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035454/
https://www.ncbi.nlm.nih.gov/pubmed/27688736
http://dx.doi.org/10.1186/s12935-016-0349-7

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