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Inhibition of complement improves graft outcome in a pig model of kidney autotransplantation

BACKGROUND: Ischemia reperfusion injury (IRI) induced immune response is a critical issue in transplantation. Complement and contact system activation are among its key mechanisms. STUDY DESIGN: We investigated the benefits of pre-reperfusion treatment with recombinant human C1INH (rhC1INH), inhibit...

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Detalles Bibliográficos
Autores principales:	Delpech, Pierre-Olivier, Thuillier, Raphael, SaintYves, Thibault, Danion, Jerome, Le Pape, Sylvain, van Amersfoort, Edwin S., Oortwijn, Beatrijs, Blancho, Gilles, Hauet, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035455/ https://www.ncbi.nlm.nih.gov/pubmed/27663514 http://dx.doi.org/10.1186/s12967-016-1013-7

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