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Identification of control targets in Boolean molecular network models via computational algebra

BACKGROUND: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more desirable, state through an intervention, such as a...

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Detalles Bibliográficos
Autores principales: Murrugarra, David, Veliz-Cuba, Alan, Aguilar, Boris, Laubenbacher, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035508/
https://www.ncbi.nlm.nih.gov/pubmed/27662842
http://dx.doi.org/10.1186/s12918-016-0332-x