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Opportunities for immunotherapy in microsatellite instable colorectal cancer

Microsatellite instability (MSI), the somatic accumulation of length variations in repetitive DNA sequences called microsatellites, is frequently observed in both hereditary and sporadic colorectal cancer (CRC). It has been established that defects in the DNA mismatch repair (MMR) pathway underlie t...

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Detalles Bibliográficos
Autores principales:	Westdorp, Harm, Fennemann, Felix L., Weren, Robbert D. A., Bisseling, Tanya M., Ligtenberg, Marjolijn J. L., Figdor, Carl G., Schreibelt, Gerty, Hoogerbrugge, Nicoline, Wimmers, Florian, de Vries, I. Jolanda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Focussed Research Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035655/ https://www.ncbi.nlm.nih.gov/pubmed/27060000 http://dx.doi.org/10.1007/s00262-016-1832-7

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