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Sustained Immune Complex-Mediated Reduction in CD16 Expression after Vaccination Regulates NK Cell Function

Cross-linking of FcγRIII (CD16) by immune complexes induces antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells, contributing to control of intracellular pathogens; this pathway can also be targeted for immunotherapy of cancerous or otherwise diseased cells. However, downreg...

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Detalles Bibliográficos
Autores principales:	Goodier, Martin R., Lusa, Chiara, Sherratt, Sam, Rodriguez-Galan, Ana, Behrens, Ron, Riley, Eleanor M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035824/ https://www.ncbi.nlm.nih.gov/pubmed/27725819 http://dx.doi.org/10.3389/fimmu.2016.00384

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