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Automated Enrichment, Transduction, and Expansion of Clinical-Scale CD62L(+) T Cells for Manufacturing of Gene Therapy Medicinal Products

Multiple clinical studies have demonstrated that adaptive immunotherapy using redirected T cells against advanced cancer has led to promising results with improved patient survival. The continuously increasing interest in those advanced gene therapy medicinal products (GTMPs) leads to a manufacturin...

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Detalles Bibliográficos
Autores principales: Priesner, Christoph, Aleksandrova, Krasimira, Esser, Ruth, Mockel-Tenbrinck, Nadine, Leise, Jana, Drechsel, Katharina, Marburger, Michael, Quaiser, Andrea, Goudeva, Lilia, Arseniev, Lubomir, Kaiser, Andrew D., Glienke, Wolfgang, Koehl, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035932/
https://www.ncbi.nlm.nih.gov/pubmed/27562135
http://dx.doi.org/10.1089/hum.2016.091