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The Life-Cycle of the HIV-1 Gag–RNA Complex

Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA...

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Autores principales: Mailler, Elodie, Bernacchi, Serena, Marquet, Roland, Paillart, Jean-Christophe, Vivet-Boudou, Valérie, Smyth, Redmond P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035962/
https://www.ncbi.nlm.nih.gov/pubmed/27626439
http://dx.doi.org/10.3390/v8090248
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author Mailler, Elodie
Bernacchi, Serena
Marquet, Roland
Paillart, Jean-Christophe
Vivet-Boudou, Valérie
Smyth, Redmond P.
author_facet Mailler, Elodie
Bernacchi, Serena
Marquet, Roland
Paillart, Jean-Christophe
Vivet-Boudou, Valérie
Smyth, Redmond P.
author_sort Mailler, Elodie
collection PubMed
description Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles.
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spelling pubmed-50359622016-09-29 The Life-Cycle of the HIV-1 Gag–RNA Complex Mailler, Elodie Bernacchi, Serena Marquet, Roland Paillart, Jean-Christophe Vivet-Boudou, Valérie Smyth, Redmond P. Viruses Review Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles. MDPI 2016-09-10 /pmc/articles/PMC5035962/ /pubmed/27626439 http://dx.doi.org/10.3390/v8090248 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mailler, Elodie
Bernacchi, Serena
Marquet, Roland
Paillart, Jean-Christophe
Vivet-Boudou, Valérie
Smyth, Redmond P.
The Life-Cycle of the HIV-1 Gag–RNA Complex
title The Life-Cycle of the HIV-1 Gag–RNA Complex
title_full The Life-Cycle of the HIV-1 Gag–RNA Complex
title_fullStr The Life-Cycle of the HIV-1 Gag–RNA Complex
title_full_unstemmed The Life-Cycle of the HIV-1 Gag–RNA Complex
title_short The Life-Cycle of the HIV-1 Gag–RNA Complex
title_sort life-cycle of the hiv-1 gag–rna complex
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035962/
https://www.ncbi.nlm.nih.gov/pubmed/27626439
http://dx.doi.org/10.3390/v8090248
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