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The Life-Cycle of the HIV-1 Gag–RNA Complex
Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035962/ https://www.ncbi.nlm.nih.gov/pubmed/27626439 http://dx.doi.org/10.3390/v8090248 |
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author | Mailler, Elodie Bernacchi, Serena Marquet, Roland Paillart, Jean-Christophe Vivet-Boudou, Valérie Smyth, Redmond P. |
author_facet | Mailler, Elodie Bernacchi, Serena Marquet, Roland Paillart, Jean-Christophe Vivet-Boudou, Valérie Smyth, Redmond P. |
author_sort | Mailler, Elodie |
collection | PubMed |
description | Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles. |
format | Online Article Text |
id | pubmed-5035962 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-50359622016-09-29 The Life-Cycle of the HIV-1 Gag–RNA Complex Mailler, Elodie Bernacchi, Serena Marquet, Roland Paillart, Jean-Christophe Vivet-Boudou, Valérie Smyth, Redmond P. Viruses Review Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles. MDPI 2016-09-10 /pmc/articles/PMC5035962/ /pubmed/27626439 http://dx.doi.org/10.3390/v8090248 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mailler, Elodie Bernacchi, Serena Marquet, Roland Paillart, Jean-Christophe Vivet-Boudou, Valérie Smyth, Redmond P. The Life-Cycle of the HIV-1 Gag–RNA Complex |
title | The Life-Cycle of the HIV-1 Gag–RNA Complex |
title_full | The Life-Cycle of the HIV-1 Gag–RNA Complex |
title_fullStr | The Life-Cycle of the HIV-1 Gag–RNA Complex |
title_full_unstemmed | The Life-Cycle of the HIV-1 Gag–RNA Complex |
title_short | The Life-Cycle of the HIV-1 Gag–RNA Complex |
title_sort | life-cycle of the hiv-1 gag–rna complex |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035962/ https://www.ncbi.nlm.nih.gov/pubmed/27626439 http://dx.doi.org/10.3390/v8090248 |
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