A general and efficient strategy for generating the stable enzymes

The local flexibility of an enzyme’s active center plays pivotal roles in catalysis, however, little is known about how the flexibility of these flexible residues affects stability. In this study, we proposed an active center stabilization (ACS) strategy to improve the kinetic thermostability of Can...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiao-Fei, Yang, Guang-Yu, Zhang, Yong, Xie, Yuan, Withers, Stephen G., Feng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036031/
https://www.ncbi.nlm.nih.gov/pubmed/27667190
http://dx.doi.org/10.1038/srep33797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036031/
https://www.ncbi.nlm.nih.gov/pubmed/27667190
http://dx.doi.org/10.1038/srep33797

Ejemplares similares