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Updates on antibody-mediated rejection in intestinal transplantation
Antibody-mediated rejection (ABMR) has increasingly emerged as an important cause of allograft loss after intestinal transplantation (ITx). Compelling evidence indicates that donor-specific antibodies can mediate and promote acute and chronic rejection after ITx. However, diagnostic criteria for ABM...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036126/ https://www.ncbi.nlm.nih.gov/pubmed/27683635 http://dx.doi.org/10.5500/wjt.v6.i3.564 |
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author | Wu, Guo-Sheng |
author_facet | Wu, Guo-Sheng |
author_sort | Wu, Guo-Sheng |
collection | PubMed |
description | Antibody-mediated rejection (ABMR) has increasingly emerged as an important cause of allograft loss after intestinal transplantation (ITx). Compelling evidence indicates that donor-specific antibodies can mediate and promote acute and chronic rejection after ITx. However, diagnostic criteria for ABMR after ITx have not been established yet and the mechanisms of antibody-mediated graft injury are not well-known. Effective approaches to prevent and treat ABMR are required to improve long-term outcomes of intestine recipients. Clearly, ABMR after ITx has become an important area for research and clinical investigation. |
format | Online Article Text |
id | pubmed-5036126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-50361262016-09-28 Updates on antibody-mediated rejection in intestinal transplantation Wu, Guo-Sheng World J Transplant Minireviews Antibody-mediated rejection (ABMR) has increasingly emerged as an important cause of allograft loss after intestinal transplantation (ITx). Compelling evidence indicates that donor-specific antibodies can mediate and promote acute and chronic rejection after ITx. However, diagnostic criteria for ABMR after ITx have not been established yet and the mechanisms of antibody-mediated graft injury are not well-known. Effective approaches to prevent and treat ABMR are required to improve long-term outcomes of intestine recipients. Clearly, ABMR after ITx has become an important area for research and clinical investigation. Baishideng Publishing Group Inc 2016-09-24 2016-09-24 /pmc/articles/PMC5036126/ /pubmed/27683635 http://dx.doi.org/10.5500/wjt.v6.i3.564 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Minireviews Wu, Guo-Sheng Updates on antibody-mediated rejection in intestinal transplantation |
title | Updates on antibody-mediated rejection in intestinal transplantation |
title_full | Updates on antibody-mediated rejection in intestinal transplantation |
title_fullStr | Updates on antibody-mediated rejection in intestinal transplantation |
title_full_unstemmed | Updates on antibody-mediated rejection in intestinal transplantation |
title_short | Updates on antibody-mediated rejection in intestinal transplantation |
title_sort | updates on antibody-mediated rejection in intestinal transplantation |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036126/ https://www.ncbi.nlm.nih.gov/pubmed/27683635 http://dx.doi.org/10.5500/wjt.v6.i3.564 |
work_keys_str_mv | AT wuguosheng updatesonantibodymediatedrejectioninintestinaltransplantation |