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Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
Sizing nanomaterials in complex biological fluids, such as blood, remains a great challenge in spite of its importance for a wide range of biomedical applications. In drug delivery, for instance, it is essential that aggregation of protein-based drugs is avoided as it may alter their efficacy or eli...
Autores principales: | Xiong, Ranhua, Vandenbroucke, Roosmarijn E., Broos, Katleen, Brans, Toon, Van Wonterghem, Elien, Libert, Claude, Demeester, Jo, De Smedt, Stefaan C., Braeckmans, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036146/ https://www.ncbi.nlm.nih.gov/pubmed/27653841 http://dx.doi.org/10.1038/ncomms12982 |
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