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An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

Chronic unresolved inflammation plays a causal role in the development of advanced atherosclerosis, but the mechanisms that prevent resolution in atherosclerosis remain unclear. Here, we use targeted mass spectrometry to identify specialized pro-resolving lipid mediators (SPM) in histologically-defi...

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Detalles Bibliográficos
Autores principales:	Fredman, Gabrielle, Hellmann, Jason, Proto, Jonathan D., Kuriakose, George, Colas, Romain A., Dorweiler, Bernhard, Connolly, E. Sander, Solomon, Robert, Jones, David M., Heyer, Eric J., Spite, Matthew, Tabas, Ira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036151/ https://www.ncbi.nlm.nih.gov/pubmed/27659679 http://dx.doi.org/10.1038/ncomms12859

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