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Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer

Aberrant T-cell factor (TCF) transcription is implicated in the majority of colorectal cancers (CRCs). TCF transcription induces epithelial–mesenchymal transition (EMT), promoting a tumor-initiating cell (TIC) phenotype characterized by increased proliferation, multidrug resistance (MDR), invasion a...

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Detalles Bibliográficos
Autores principales:	Zhou, Q, Abraham, A D, Li, L, Babalmorad, A, Bagby, S, Arcaroli, J J, Hansen, R J, Valeriote, F A, Gustafson, D L, Schaack, J, Messersmith, W A, LaBarbera, D V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036162/ https://www.ncbi.nlm.nih.gov/pubmed/26947016 http://dx.doi.org/10.1038/onc.2016.29

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