Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice

Lipin-1 is a phosphatidate phosphohydrolase (PAP) required for the generation of diacylglycerol during glycerolipid synthesis, and exhibits dual functions in the regulation of lipid metabolism. Lipin-1 has been implicated in the pathogenesis of alcoholic liver disease (ALD). In the present study, we...

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Detalles Bibliográficos
Autores principales: Wang, Jiayou, Kim, Chunki, Jogasuria, Alvin, Han, Yoonhee, Hu, Xudong, Wu, Jiashin, Shen, Hong, Chrast, Roman, Finck, Brian N., You, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036185/
https://www.ncbi.nlm.nih.gov/pubmed/27666676
http://dx.doi.org/10.1038/srep34117

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