Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists

Knockout mice studies implicate the mammalian short-chain fatty acid (SCFA) receptors, FFAR2 and FFAR3– in colitis, arthritis and asthma. However, the correlation with human biology is uncertain. Here, we detected FFAR2 and FFAR3 expression in human monocytes via immunohistochemistry. Upon treatment...

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Detalles Bibliográficos
Autores principales: Ang, Zhiwei, Er, Jun Zhi, Tan, Nguan Soon, Lu, Jinhua, Liou, Yih-Cherng, Grosse, Johannes, Ding, Jeak Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036191/
https://www.ncbi.nlm.nih.gov/pubmed/27667443
http://dx.doi.org/10.1038/srep34145

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