Cargando…

LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours

OBJECTIVES: The relative contributions of inflammatory signalling and sequential oncogenic dysregulation driving liver cancer pathogenesis remain incompletely understood. Lymphotoxin-β receptor (LTβR) signalling is critically involved in hepatitis and liver tumorigenesis. Therefore, we explored the...

Descripción completa

Detalles Bibliográficos
Autores principales: Scarzello, Anthony J, Jiang, Qun, Back, Timothy, Dang, Hien, Hodge, Deborah, Hanson, Charlotte, Subleski, Jeffrey, Weiss, Jonathan M, Stauffer, Jimmy K, Chaisaingmongkol, Jitti, Rabibhadana, Siritida, Ruchirawat, Mathuros, Ortaldo, John, Wang, Xin Wei, Norris, Paula S, Ware, Carl F, Wiltrout, Robert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036232/
https://www.ncbi.nlm.nih.gov/pubmed/26206664
http://dx.doi.org/10.1136/gutjnl-2014-308810

Ejemplares similares