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In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome

OBJECTIVE: Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many patients, but treatment failure can occur which has been associated with the a...

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Detalles Bibliográficos
Autores principales:	Todt, Daniel, Gisa, Anett, Radonic, Aleksandar, Nitsche, Andreas, Behrendt, Patrick, Suneetha, Pothakamuri Venkata, Pischke, Sven, Bremer, Birgit, Brown, Richard J P, Manns, Michael P, Cornberg, Markus, Bock, C Thomas, Steinmann, Eike, Wedemeyer, Heiner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036239/ https://www.ncbi.nlm.nih.gov/pubmed/27222534 http://dx.doi.org/10.1136/gutjnl-2015-311000

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