Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection

OBJECTIVE: HCV infection affects millions of people worldwide, and many patients develop chronic infection leading to liver cancers. For decades, the lack of a small animal model that can recapitulate HCV infection, its immunopathogenesis and disease progression has impeded the development of an eff...

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Detalles Bibliográficos
Autores principales: Keng, Choong Tat, Sze, Ching Wooen, Zheng, Dahai, Zheng, Zhiqiang, Yong, Kylie Su Mei, Tan, Shu Qi, Ong, Jessica Jie Ying, Tan, Sue Yee, Loh, Eva, Upadya, Megha Haridas, Kuick, Chik Hong, Hotta, Hak, Lim, Seng Gee, Tan, Thiam Chye, Chang, Kenneth T E, Hong, Wanjin, Chen, Jianzhu, Tan, Yee-Joo, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036242/
https://www.ncbi.nlm.nih.gov/pubmed/26149491
http://dx.doi.org/10.1136/gutjnl-2014-307856

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