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Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis
OBJECTIVES: We investigated whether citrullinated tenascin-C (cTNC), an extracellular matrix protein expressed at high levels in the joints of patients with rheumatoid arthritis (RA), is a target for the autoantibodies in RA. METHODS: Citrullinated sites were mapped by mass spectrometry in the fibri...
Autores principales: | Schwenzer, Anja, Jiang, Xia, Mikuls, Ted R, Payne, Jeffrey B, Sayles, Harlan R, Quirke, Anne-Marie, Kessler, Benedikt M, Fischer, Roman, Venables, Patrick J, Lundberg, Karin, Midwood, Kim S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036245/ https://www.ncbi.nlm.nih.gov/pubmed/26659718 http://dx.doi.org/10.1136/annrheumdis-2015-208495 |
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