Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates

BACKGROUND: Interleukin-15 is an immunostimulatory cytokine overexpressed in several autoimmune and inflammatory diseases such as Rheumatoid Arthritis, psoriasis and ulcerative colitis; thus, inhibition of IL-15-induced signaling could be clinically beneficial in these disorders. Our approach to neu...

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Detalles Bibliográficos
Autores principales: Rodríguez-Álvarez, Yunier, Morera-Díaz, Yanelys, Gerónimo-Pérez, Haydee, Castro-Velazco, Jorge, Martínez-Castillo, Rafael, Puente-Pérez, Pedro, Besada-Pérez, Vladimir, Hardy-Rando, Eugenio, Chico-Capote, Araceli, Martínez-Cordovez, Klaudia, Santos-Savio, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036325/
https://www.ncbi.nlm.nih.gov/pubmed/27671547
http://dx.doi.org/10.1186/s12865-016-0168-6

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