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Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study
BACKGROUND: A fixed-dose combination (FDC) of amlodipine and losartan has been used to reduce blood pressure in patients whose hypertension is not sufficiently controlled with either drug alone. The aim of this study was to evaluate the pharmacokinetic (PK) characteristics and tolerability of an FDC...
Autores principales: | Choi, YoonJung, Lee, SeungHwan, Cho, Sang-Min, Kang, Won-Ho, Nam, Kyu-Yeol, Jang, In-Jin, Yu, Kyung-Sang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036556/ https://www.ncbi.nlm.nih.gov/pubmed/27703330 http://dx.doi.org/10.2147/DDDT.S113891 |
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