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Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia
BACKGROUND: Modulation of inflammation and oxidative stress appears to limit sepsis-induced damage in experimental models. The kidney is one of the most sensitive organs to injury during septic shock. In this study, we evaluated the effect of N-acetylcysteine (NAC) administration in conjunction with...
Autores principales: | Ergin, Bulent, Guerci, Philippe, Zafrani, Lara, Nocken, Frank, Kandil, Asli, Gurel-Gurevin, Ebru, Demirci-Tansel, Cihan, Ince, Can |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037099/ https://www.ncbi.nlm.nih.gov/pubmed/27671340 http://dx.doi.org/10.1186/s40635-016-0106-1 |
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