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Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages

The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, &qu...

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Autores principales: Ruiz-González, M.D., Cañete, M.D., Gómez-Chaparro, J.L., Rodríguez-Torronteras, A., Abril, N., Cañete, R., López-Barea, J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037120/
https://www.ncbi.nlm.nih.gov/pubmed/27699198
http://dx.doi.org/10.1016/j.dib.2016.09.024
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author Ruiz-González, M.D.
Cañete, M.D.
Gómez-Chaparro, J.L.
Rodríguez-Torronteras, A.
Abril, N.
Cañete, R.
López-Barea, J.L.
author_facet Ruiz-González, M.D.
Cañete, M.D.
Gómez-Chaparro, J.L.
Rodríguez-Torronteras, A.
Abril, N.
Cañete, R.
López-Barea, J.L.
author_sort Ruiz-González, M.D.
collection PubMed
description The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, "Very Preterm" 29–32 weeks, "Moderate Preterm" 33–36 weeks, and, "Term" ≥37weeks. From each newborn, blood was drawn three times from birth to 1 month life. High-abundant serum proteins were depleted, and the minority ones were separated by 2DE and analyzed for significant expression differences. The data reflect analytic and clinic variables analyzed globally and categorized by gestational age in relation to IUGR and the optimization of conditions for 2-DE separation. The data from this study are related to the research article entitled "Alterations of Protein Expression in Serum of Infants with Intrauterine Growth Restriction and Different Gestational Ages" (M.D. Ruis-González, M.D. Cañete, J.L. Gómez-Chaparro, N. Abril, R. Cañete, J. López-Barea, 2015) [1]. The present dataset of serum IUGR newborn proteome can be used as a reference for any study involving intrauterine growth restriction during the first month of life.
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spelling pubmed-50371202016-10-03 Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages Ruiz-González, M.D. Cañete, M.D. Gómez-Chaparro, J.L. Rodríguez-Torronteras, A. Abril, N. Cañete, R. López-Barea, J.L. Data Brief Data Article The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, "Very Preterm" 29–32 weeks, "Moderate Preterm" 33–36 weeks, and, "Term" ≥37weeks. From each newborn, blood was drawn three times from birth to 1 month life. High-abundant serum proteins were depleted, and the minority ones were separated by 2DE and analyzed for significant expression differences. The data reflect analytic and clinic variables analyzed globally and categorized by gestational age in relation to IUGR and the optimization of conditions for 2-DE separation. The data from this study are related to the research article entitled "Alterations of Protein Expression in Serum of Infants with Intrauterine Growth Restriction and Different Gestational Ages" (M.D. Ruis-González, M.D. Cañete, J.L. Gómez-Chaparro, N. Abril, R. Cañete, J. López-Barea, 2015) [1]. The present dataset of serum IUGR newborn proteome can be used as a reference for any study involving intrauterine growth restriction during the first month of life. Elsevier 2016-09-21 /pmc/articles/PMC5037120/ /pubmed/27699198 http://dx.doi.org/10.1016/j.dib.2016.09.024 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Ruiz-González, M.D.
Cañete, M.D.
Gómez-Chaparro, J.L.
Rodríguez-Torronteras, A.
Abril, N.
Cañete, R.
López-Barea, J.L.
Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_full Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_fullStr Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_full_unstemmed Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_short Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_sort morbility, clinical data and proteomic analysis of iugr and aga newborns at different gestational ages
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037120/
https://www.ncbi.nlm.nih.gov/pubmed/27699198
http://dx.doi.org/10.1016/j.dib.2016.09.024
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