Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

Guanylin (GN) and uroguanylin (UGN), through activation of guanylyl cyclase C (GCC), serve to control intestinal fluid homeostasis. Both peptides are produced in the intestinal epithelium, but their cellular origin has not been fully charted. Using quantitative PCR and an improved in situ hybridizat...

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Detalles Bibliográficos
Autores principales: Ikpa, Pauline T., Sleddens, Hein F. B. M., Steinbrecher, Kris A., Peppelenbosch, Maikel P., de Jonge, Hugo R., Smits, Ron, Bijvelds, Marcel J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037145/
https://www.ncbi.nlm.nih.gov/pubmed/27246004
http://dx.doi.org/10.1007/s00418-016-1453-4

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