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Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique
This study was conducted to establish the feasibility of corneal transplantation using the big-bubble technique (BBT) to perform deep anterior lamellar keratoplasty (DALK) in three dogs. After the cornea was trephined 750 µm, 4 mL of air was injected, and the blanched stroma was removed to expose De...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Veterinary Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037302/ https://www.ncbi.nlm.nih.gov/pubmed/26645335 http://dx.doi.org/10.4142/jvs.2016.17.3.347 |
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author | Kim, Soohyun Kwak, Ji Yoon Jeong, Manbok Seo, Kangmoon |
author_facet | Kim, Soohyun Kwak, Ji Yoon Jeong, Manbok Seo, Kangmoon |
author_sort | Kim, Soohyun |
collection | PubMed |
description | This study was conducted to establish the feasibility of corneal transplantation using the big-bubble technique (BBT) to perform deep anterior lamellar keratoplasty (DALK) in three dogs. After the cornea was trephined 750 µm, 4 mL of air was injected, and the blanched stroma was removed to expose Descemet's membrane (DM). The donor corneal button, which was gently stripped off the DM, was sutured onto the bare DM of the recipient cornea. The dogs received topical antibiotics every 6 h for 7 days and 2% cyclosporine ointment every 12 h for 1 month. The eyes were examined post-operatively at 7, 14, 21, 28 and 150 days. The central portion of the transplanted cornea stayed transparent while corneal haze developed around the transplanted margin. Menace response was normal even though the transplanted cornea was edematous until 3 weeks after surgery. A marginal haze was rarely observed between the donor and recipient corneas at 150 days after the operation. A spotted haze developed in the central part of the deep stroma near the DM. Upon histopathological examination, the stroma and epithelium of the donor cornea had normal structures. Corneal transplantation using DALK with BBT can be performed in dogs preserving the healthy endothelium. |
format | Online Article Text |
id | pubmed-5037302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-50373022016-09-29 Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique Kim, Soohyun Kwak, Ji Yoon Jeong, Manbok Seo, Kangmoon J Vet Sci Original Article This study was conducted to establish the feasibility of corneal transplantation using the big-bubble technique (BBT) to perform deep anterior lamellar keratoplasty (DALK) in three dogs. After the cornea was trephined 750 µm, 4 mL of air was injected, and the blanched stroma was removed to expose Descemet's membrane (DM). The donor corneal button, which was gently stripped off the DM, was sutured onto the bare DM of the recipient cornea. The dogs received topical antibiotics every 6 h for 7 days and 2% cyclosporine ointment every 12 h for 1 month. The eyes were examined post-operatively at 7, 14, 21, 28 and 150 days. The central portion of the transplanted cornea stayed transparent while corneal haze developed around the transplanted margin. Menace response was normal even though the transplanted cornea was edematous until 3 weeks after surgery. A marginal haze was rarely observed between the donor and recipient corneas at 150 days after the operation. A spotted haze developed in the central part of the deep stroma near the DM. Upon histopathological examination, the stroma and epithelium of the donor cornea had normal structures. Corneal transplantation using DALK with BBT can be performed in dogs preserving the healthy endothelium. The Korean Society of Veterinary Science 2016-09 2016-09-20 /pmc/articles/PMC5037302/ /pubmed/26645335 http://dx.doi.org/10.4142/jvs.2016.17.3.347 Text en © 2016 The Korean Society of Veterinary Science. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Soohyun Kwak, Ji Yoon Jeong, Manbok Seo, Kangmoon Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title | Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title_full | Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title_fullStr | Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title_full_unstemmed | Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title_short | Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
title_sort | deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037302/ https://www.ncbi.nlm.nih.gov/pubmed/26645335 http://dx.doi.org/10.4142/jvs.2016.17.3.347 |
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