BK channel agonist represents a potential therapeutic approach for lysosomal storage diseases

Efficient lysosomal Ca(2+) release plays an essential role in lysosomal trafficking. We have recently shown that lysosomal big conductance Ca(2+)-activated potassium (BK) channel forms a physical and functional coupling with the lysosomal Ca(2+) release channel Transient Receptor Potential Mucolipin...

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Detalles Bibliográficos
Autores principales: Zhong, Xi Zoë, Sun, Xue, Cao, Qi, Dong, Gaofeng, Schiffmann, Raphael, Dong, Xian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037385/
https://www.ncbi.nlm.nih.gov/pubmed/27670435
http://dx.doi.org/10.1038/srep33684

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