Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

Morphogenesis of the vascular system is strongly modulated by mechanical forces from blood flow. Hereditary hemorrhagic telangiectasia (HHT) is an inherited autosomal-dominant disease in which arteriovenous malformations and telangiectasias accumulate with age. Most cases are linked to heterozygous...

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Detalles Bibliográficos
Autores principales: Baeyens, Nicolas, Larrivée, Bruno, Ola, Roxana, Hayward-Piatkowskyi, Brielle, Dubrac, Alexandre, Huang, Billy, Ross, Tyler D., Coon, Brian G., Min, Elizabeth, Tsarfati, Maya, Tong, Haibin, Eichmann, Anne, Schwartz, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037412/
https://www.ncbi.nlm.nih.gov/pubmed/27646277
http://dx.doi.org/10.1083/jcb.201603106

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