Shedding light on paraspeckle structure by super-resolution microscopy

The nuclear body paraspeckle is built on the lncRNA Neat1 and plays important roles in gene regulation. In this issue, West et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601071) use super-resolution structured illumination microscopy to show that paraspeckles are organized in a core-s...

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Detalles Bibliográficos
Autores principales: Hu, Shi-Bin, Yao, Run-Wen, Chen, Ling-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037413/
https://www.ncbi.nlm.nih.gov/pubmed/27646270
http://dx.doi.org/10.1083/jcb.201609008
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author Hu, Shi-Bin
Yao, Run-Wen
Chen, Ling-Ling
author_facet Hu, Shi-Bin
Yao, Run-Wen
Chen, Ling-Ling
author_sort Hu, Shi-Bin
collection PubMed
description The nuclear body paraspeckle is built on the lncRNA Neat1 and plays important roles in gene regulation. In this issue, West et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601071) use super-resolution structured illumination microscopy to show that paraspeckles are organized in a core-shell spheroidal structure composed of Neat1 and seven proteins.
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spelling pubmed-50374132017-03-26 Shedding light on paraspeckle structure by super-resolution microscopy Hu, Shi-Bin Yao, Run-Wen Chen, Ling-Ling J Cell Biol Commentary The nuclear body paraspeckle is built on the lncRNA Neat1 and plays important roles in gene regulation. In this issue, West et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601071) use super-resolution structured illumination microscopy to show that paraspeckles are organized in a core-shell spheroidal structure composed of Neat1 and seven proteins. The Rockefeller University Press 2016-09-26 /pmc/articles/PMC5037413/ /pubmed/27646270 http://dx.doi.org/10.1083/jcb.201609008 Text en © 2016 Hu et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Hu, Shi-Bin
Yao, Run-Wen
Chen, Ling-Ling
Shedding light on paraspeckle structure by super-resolution microscopy
title Shedding light on paraspeckle structure by super-resolution microscopy
title_full Shedding light on paraspeckle structure by super-resolution microscopy
title_fullStr Shedding light on paraspeckle structure by super-resolution microscopy
title_full_unstemmed Shedding light on paraspeckle structure by super-resolution microscopy
title_short Shedding light on paraspeckle structure by super-resolution microscopy
title_sort shedding light on paraspeckle structure by super-resolution microscopy
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037413/
https://www.ncbi.nlm.nih.gov/pubmed/27646270
http://dx.doi.org/10.1083/jcb.201609008
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