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Blood flow boosts BMP signaling to keep vessels in shape

Bone morphogenic proteins (BMPs) and blood flow regulate vascular remodeling and homeostasis. In this issue, Baeyens et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603106) show that blood flow sensitizes endothelial cells to BMP9 signaling by triggering Alk1/ENG complexing to suppress...

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Detalles Bibliográficos
Autores principales: Franco, Claudio A., Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037414/
https://www.ncbi.nlm.nih.gov/pubmed/27672213
http://dx.doi.org/10.1083/jcb.201609038