Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications

The pattern recognition receptor TLR4 is well known as a crucial receptor during infection and inflammation. Several TLR4 antagonists have been reported to inhibit the function of TLR4. Both natural occurring antagonists, lipopolysaccharide (LPS) from Gram-negative bacteria as well as synthetic comp...

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Detalles Bibliográficos
Autores principales: Malgorzata-Miller, Gosia, Heinbockel, Lena, Brandenburg, Klaus, van der Meer, Jos W. M., Netea, Mihai G., Joosten, Leo A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037446/
https://www.ncbi.nlm.nih.gov/pubmed/27670746
http://dx.doi.org/10.1038/srep34221

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