CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes

Antibody-dependent cellular cytotoxicity (ADCC) is exerted by immune cells expressing surface Fcγ receptors (FcγRs) against cells coated with antibody, such as virus-infected or transformed cells. CD16, the FcγRIIIA, is essential for ADCC by NK cells, and is also expressed by a subset of human blood...

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Detalles Bibliográficos
Autores principales: Yeap, Wei Hseun, Wong, Kok Loon, Shimasaki, Noriko, Teo, Esmeralda Chi Yuan, Quek, Jeffrey Kim Siang, Yong, Hao Xiang, Diong, Colin Phipps, Bertoletti, Antonio, Linn, Yeh Ching, Wong, Siew Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037471/
https://www.ncbi.nlm.nih.gov/pubmed/27670158
http://dx.doi.org/10.1038/srep34310

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