Cargando…

Tetanus Neurotoxin Neutralizing Antibodies Screened from a Human Immune scFv Antibody Phage Display Library

Tetanus neurotoxin (TeNT) produced by Clostridium tetani is one of the most poisonous protein substances. Neutralizing antibodies against TeNT can effectively prevent and cure toxicosis. Using purified Hc fragments of TeNT (TeNT-Hc) as an antigen, three specific neutralizing antibody clones recogniz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Han, Yu, Rui, Fang, Ting, Yu, Ting, Chi, Xiangyang, Zhang, Xiaopeng, Liu, Shuling, Fu, Ling, Yu, Changming, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037492/ https://www.ncbi.nlm.nih.gov/pubmed/27626445 http://dx.doi.org/10.3390/toxins8090266

Ejemplares similares

A compact phage display human scFv library for selection of antibodies to a wide variety of antigens
por: Pansri, Potjamas, et al.
Publicado: (2009)

Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery
por: Liu, Jing, et al.
Publicado: (2016)

Neutralizing human recombinant antibodies against herpes simplex virus type 1 glycoproteins B from a phage-displayed scFv antibody library
por: Bagheri, Vahid, et al.
Publicado: (2017)

scFv Antibody: Principles and Clinical Application
por: Ahmad, Zuhaida Asra, et al.
Publicado: (2012)

Construction and application of a human scFv phage display library based on Cre-LoxP recombination for anti-PCSK9 antibody selection
por: Dong, Yuan, et al.
Publicado: (2021)

Clonal array profiling of scFv-displaying phages for high-throughput discovery of affinity-matured antibody mutants
por: Kiguchi, Yuki, et al.
Publicado: (2020)

Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E
por: Miethe, Sebastian, et al.
Publicado: (2015)

Isolation and characterization of phage display-derived scFv antibodies against human parechovirus 1 VP0 protein
por: Hietanen, Eero, et al.
Publicado: (2022)

Implementation of a Design of Experiments to Improve Periplasmic Yield of Functional ScFv Antibodies in a Phage Display Platform
por: Aghdam, Marjan Abri, et al.
Publicado: (2022)

Generation of a mouse scFv library specific for porcine aminopeptidase N using the T7 phage display system
por: Sun, Dongbo, et al.
Publicado: (2012)

Screening Antibody Libraries with Colony Assay Using scFv-Alkaline Phosphatase Fusion Proteins
por: Hanyu, Yoshiro, et al.
Publicado: (2020)

Broad specificity of immune helminth scFv library to identify monoclonal antibodies targeting Strongyloides
por: Rahumatullah, Anizah, et al.
Publicado: (2021)

Baculovirus display of single chain antibody (scFv) using a novel signal peptide
por: Kitidee, Kuntida, et al.
Publicado: (2010)

Discovery of Hapten-Specific scFv from a Phage Display Library and Applications for HER2-Positive Tumor Imaging
por: Kim, Hye-Yeong, et al.
Publicado: (2014)

Characterization and analysis of scFv-IgG bispecific antibody size variants
por: Cao, Mingyan, et al.
Publicado: (2018)

Selection and characterization of high affinity VEGFR1 antibodies from a novel human binary code scFv phage library
por: Wang, Xiaolei, et al.
Publicado: (2015)

Targeting the active site of the placental isozyme of alkaline phosphatase by phage-displayed scFv antibodies selected by a specific uncompetitive inhibitor
por: Saini, Deepti, et al.
Publicado: (2005)

Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display
por: Keller, Thomas, et al.
Publicado: (2015)

Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy
por: Ghaderi, Sepideh Safaei, et al.
Publicado: (2022)

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library
por: Miethe, Sebastian, et al.
Publicado: (2014)

Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library
por: Li, Yonghai, et al.
Publicado: (2012)

A scFv Phage Display Mini Library Generated from the Immunoglobulin Repertoire of Breast Medullary Carcinoma Infiltrating B Lymphocytes
por: Kotlan, B., et al.
Publicado: (2000)

Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
por: Goffinet, Marine, et al.
Publicado: (2008)

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments
por: Nannini, Francesco, et al.
Publicado: (2020)

Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays
por: Chan, Conrad E.Z., et al.
Publicado: (2011)

The Four-State Equilibrium Unfolding of a scFv Antibody Fragment
por: Pedroso, Idolka, et al.
Publicado: (2002)

Humanization and directed evolution of the selenium-containing scFv phage abzyme
por: Xu, Yan, et al.
Publicado: (2018)

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion
por: Ascione, Alessandro, et al.
Publicado: (2019)

Isolation and characterization of human anti-CD20 single-chain variable fragment (scFv) from a Naive human scFv library
por: Shams, Nasir, et al.
Publicado: (2022)

An innovative flow cytometry method to screen human scFv-phages selected by in vivo phage-display in an animal model of atherosclerosis
por: Hemadou, Audrey, et al.
Publicado: (2018)

Relative Contribution of Framework and CDR Regions in Antibody Variable Domains to Multimerisation of Fv- and scFv-Containing Bispecific Antibodies
por: Bhatta, Pallavi, et al.
Publicado: (2018)

Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy
por: Sørensen, Christoffer V., et al.
Publicado: (2023)

Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries
por: Han, Seung Yub, et al.
Publicado: (2018)

Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity
por: Pelat, Thibaut, et al.
Publicado: (2009)

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B
por: Rasetti-Escargueil, Christine, et al.
Publicado: (2015)

Designing antibody against highly conserved region of dengue envelope protein by in silico screening of scFv mutant library
por: Rathore, Abhishek Singh, et al.
Publicado: (2019)

Development of Anti-LRRC15 Small Fragments for Imaging Purposes Using a Phage-Display ScFv Approach
por: Baurand, Pierre-Emmanuel, et al.
Publicado: (2022)

Identification of Potent CD19 scFv for CAR T Cells through scFv Screening with NK/T-Cell Line
por: Kang, Chung Hyo, et al.
Publicado: (2020)

Diversity of the Antibody Response to Tetanus Toxoid: Comparison of Hybridoma Library to Phage Display Library
por: Sorouri, Mahsa, et al.
Publicado: (2014)

Bioinformatics in molecular immunology laboratories demonstrated: Modeling an anti-CMV scFv antibody
por: Heng, Chua Kek, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_s2gmrbug8rk7b84i0476nvio62