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Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549)

We investigated the toxicity of benzo[a]pyrene (B[a]P), 1-nitropyrene (1-NP) and 3-nitrobenzanthrone (3-NBA) in A549 cells. Cells were treated for 4 h and 24 h with: B[a]P (0.1 and 1 μM), 1-NP (1 and 10 μM) and 3-NBA (0.5 and 5 μM). Bulky DNA adducts, lipid peroxidation, DNA and protein oxidation an...

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Detalles Bibliográficos
Autores principales:	Rossner, Pavel, Strapacova, Simona, Stolcpartova, Jitka, Schmuczerova, Jana, Milcova, Alena, Neca, Jiri, Vlkova, Veronika, Brzicova, Tana, Machala, Miroslav, Topinka, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037673/ https://www.ncbi.nlm.nih.gov/pubmed/27571070 http://dx.doi.org/10.3390/ijms17091393

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