Cargando…

TLR4-Activated MAPK-IL-6 Axis Regulates Vascular Smooth Muscle Cell Function

Migration of vascular smooth muscle cells (VSMCs) into the intima is considered to be a vital event in the pathophysiology of atherosclerosis. Despite substantial evidence supporting the pathogenic role of Toll-like receptor 4 (TLR4) in the progression of atherogenesis, its function in the regulatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Guan-Lin, Wu, Jing-Yiing, Tsai, Chien-Sung, Lin, Chih-Yuan, Tsai, Yi-Ting, Lin, Chin-Sheng, Wang, Yi-Fu, Yet, Shaw-Fang, Hsu, Yu-Juei, Kuo, Cheng-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037674/ https://www.ncbi.nlm.nih.gov/pubmed/27563891 http://dx.doi.org/10.3390/ijms17091394

Ejemplares similares

Tryptophan metabolite 5-methoxytryptophan ameliorates arterial denudation-induced intimal hyperplasia via opposing effects on vascular endothelial and smooth muscle cells
por: Chen, Chung-Huang, et al.
Publicado: (2019)

Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia
por: Lu, Yi-Jhu, et al.
Publicado: (2020)

Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols
por: Ho, Chia-Chi, et al.
Publicado: (2021)

A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury
por: Ho, Yen-Chun, et al.
Publicado: (2016)

Association of Serum Phosphate with Low Handgrip Strength in Patients with Advanced Chronic Kidney Disease
por: Tsai, Ping-Huang, et al.
Publicado: (2021)

Glossogyne tenuifolia Attenuates Proliferation and Migration of Vascular Smooth Muscle Cells
por: Hsuan, Chin-Feng, et al.
Publicado: (2020)

Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1
por: Lee, Chien-Hsing, et al.
Publicado: (2017)

miR-424/322 protects against abdominal aortic aneurysm formation by modulating the Smad2/3/runt-related transcription factor 2 axis
por: Tsai, Hsiao-Ya, et al.
Publicado: (2021)

TLR9-mediated ARF6 activation is involved in advancing CpG ODN cellular uptake
por: Wu, Jing-Yiing, et al.
Publicado: (2012)

Hepatocellular carcinoma-derived high mobility group box 1 triggers M2 macrophage polarization via a TLR2/NOX2/autophagy axis
por: Shiau, Dong-Jer, et al.
Publicado: (2020)

Montelukast Increased IL-25, IL-33, and TSLP via Epigenetic Regulation in Airway Epithelial Cells
por: Tsai, Mei-Lan, et al.
Publicado: (2023)

Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics
por: Tsai, Min-Shao, et al.
Publicado: (2018)

Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE(−/−) mice fed high fat diet
por: Lee, Guan-Lin, et al.
Publicado: (2021)

Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production
por: Yeh, Chang-Ching, et al.
Publicado: (2019)

Rosmarinic Acid Attenuates the Lipopolysaccharide-Provoked Inflammatory Response of Vascular Smooth Muscle Cell via Inhibition of MAPK/NF-κB Cascade
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Alterations of RET, Oncogene in Human Adrenal Tumors
por: Lin, Shiu‐Ru, et al.
Publicado: (1998)

Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker
por: Ho, Chia-Chi, et al.
Publicado: (2022)

5-methoxytryptophan: an arsenal against vascular injury and inflammation
por: Wu, Kenneth K., et al.
Publicado: (2020)

Resistin enhances angiogenesis in osteosarcoma via the MAPK signaling pathway
por: Tsai, Hsiao-Chi, et al.
Publicado: (2019)

Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells
por: Chang, Jia-Feng, et al.
Publicado: (2022)

Porphyromonas gingivalis Lipopolysaccharides Promote Proliferation and Migration of Human Vascular Smooth Muscle Cells through the MAPK/TLR4 Pathway
por: Miyabe, Megumi, et al.
Publicado: (2022)

The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage
por: Lin, You-Sheng, et al.
Publicado: (2023)

The regulation of NLRP3 inflammasome expression during the development of cardiac contractile dysfunction in chronic kidney disease
por: Chin, Li-Han, et al.
Publicado: (2017)

Incidence and clinical features of patients with peritoneal dialysis peritonitis complicated by bacteremia
por: Tsai, Chang-Chih, et al.
Publicado: (2018)

The CCL2/CCR2 Axis Enhances Vascular Cell Adhesion Molecule-1 Expression in Human Synovial Fibroblasts
por: Lin, Yu-Min, et al.
Publicado: (2012)

IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy
por: Tsai, Mei-Lan, et al.
Publicado: (2021)

The molecular and clinical verification of therapeutic resistance via the p38 MAPK–Hsp27 axis in lung cancer
por: Liu, Chia-Lin, et al.
Publicado: (2016)

Garlic Oil Alleviates MAPKs- and IL-6-mediated Diabetes-related Cardiac Hypertrophy in STZ-induced DM Rats
por: Chang, Sheng-Huang, et al.
Publicado: (2011)

Micrometer Backstepping Control System for Linear Motion Single Axis Robot Machine Drive
por: Lin, Chih-Hong, et al.
Publicado: (2019)

IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1
por: Wu, Wan-Ju, et al.
Publicado: (2021)

Targeting spike protein-induced TLR/NET axis by COVID-19 therapeutic NRICM102 ameliorates pulmonary embolism and fibrosis
por: Wei, Wen-Chi, et al.
Publicado: (2022)

Off-pump beating coronary artery bypass grafting in a young adult with Kawasaki disease
por: Hsu, Kuo-Feng, et al.
Publicado: (2008)

Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice
por: Hung, Yi-Han, et al.
Publicado: (2016)

Plasma levels of IL-1β and IL-37 in patients with severe haemophilia
por: Lin, Pei-Chin, et al.
Publicado: (2020)

S1P promotes IL-6 expression in osteoblasts through the PI3K, MEK/ERK and NF-κB signaling pathways
por: Hu, Sung-Lin, et al.
Publicado: (2020)

Genistein suppresses leptin‐induced proliferation and migration of vascular smooth muscle cells and neointima formation
por: Tsai, Yung‐Chieh, et al.
Publicado: (2016)

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
por: Liu, Yan Zhong, et al.
Publicado: (2022)

Scavenging Intracellular ROS Attenuates p-Cresyl Sulfate-Triggered Osteogenesis through MAPK Signaling Pathway and NF-κB Activation in Human Arterial Smooth Muscle Cells
por: Chang, Jia-Feng, et al.
Publicado: (2020)

Hepatocyte Growth Factor Increases Vascular Endothelial Growth Factor-A Production in Human Synovial Fibroblasts through c-Met Receptor Pathway
por: Lin, Yu-Min, et al.
Publicado: (2012)

Divergent signaling pathways cooperatively regulate TGFβ induction of cysteine-rich protein 2 in vascular smooth muscle cells
por: Wu, Meng-Ling, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ff4un05b6judfgq3uu2jnd7hf8