Efficacy of Polyvalent Human Immunoglobulins in an Animal Model of Neuromyelitis Optica Evoked by Intrathecal Anti-Aquaporin 4 Antibodies

Neuromyelitis Optica Spectrum Disorders (NMOSD) are associated with autoantibodies (ABs) targeting the astrocytic aquaporin-4 water channels (AQP4-ABs). These ABs have a direct pathogenic role by initiating a variety of immunological and inflammatory processes in the course of disease. In a recently...

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Detalles Bibliográficos
Autores principales: Grünewald, Benedikt, Bennett, Jeffrey L., Toyka, Klaus V., Sommer, Claudia, Geis, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037687/
https://www.ncbi.nlm.nih.gov/pubmed/27571069
http://dx.doi.org/10.3390/ijms17091407

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