Cargando…

Lipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and Hypoxia

The Warburg effect describes the phenomenon by which cancer cells obtain energy from glycolysis even under normoxic (O(2)-sufficient) conditions. Tumor tissues are generally exposed to hypoxia owing to inefficient and aberrant vasculature. Cancer cells have multiple molecular mechanisms to adapt to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koizume, Shiro, Miyagi, Yohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037709/ https://www.ncbi.nlm.nih.gov/pubmed/27589734 http://dx.doi.org/10.3390/ijms17091430

Ejemplares similares

Anti-apoptotic genes are synergistically activated in OVSAYO cells cultured under conditions of serum starvation and hypoxia
por: Koizume, Shiro, et al.
Publicado: (2015)

Tissue Factor–Factor VII Complex As a Key Regulator of Ovarian Cancer Phenotypes
por: Koizume, Shiro, et al.
Publicado: (2015)

The lipid droplet: A conserved cellular organelle
por: Zhang, Congyan, et al.
Publicado: (2017)

Lipid Droplets: A Cellular Organelle Vital for Thermogenesis
por: Chen, Lupeng, et al.
Publicado: (2022)

Tissue factor in cancer-associated thromboembolism: possible mechanisms and clinical applications
por: Koizume, Shiro, et al.
Publicado: (2022)

Potential Coagulation Factor-Driven Pro-Inflammatory Responses in Ovarian Cancer Tissues Associated with Insufficient O(2) and Plasma Supply
por: Koizume, Shiro, et al.
Publicado: (2017)

Lipid droplets: a cellular organelle vital in cancer cells
por: Jin, Yi, et al.
Publicado: (2023)

Diverse Mechanisms of Sp1-Dependent Transcriptional Regulation Potentially Involved in the Adaptive Response of Cancer Cells to Oxygen-Deficient Conditions
por: Koizume, Shiro, et al.
Publicado: (2015)

Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer
por: Koizume, Shiro, et al.
Publicado: (2015)

Modeling Direct and Indirect Action on Cell Survival After Photon Irradiation under Normoxia and Hypoxia
por: Liew, Hans, et al.
Publicado: (2020)

Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association
por: Mahamid, Julia, et al.
Publicado: (2019)

Authors' reply to the Letter to the Editor: Tissue factor and its procoagulant activity on cancer‐associated thromboembolism in pancreatic cancer
por: Koizume, Shiro, et al.
Publicado: (2022)

The lipid droplet—a well-connected organelle
por: Gao, Qiang, et al.
Publicado: (2015)

Friend or Foe: Lipid Droplets as Organelles for Protein and Lipid Storage in Cellular Stress Response, Aging and Disease
por: Geltinger, Florian, et al.
Publicado: (2020)

Lactic Acidosis Promotes Mitochondrial Biogenesis in Lung Adenocarcinoma Cells, Supporting Proliferation Under Normoxia or Survival Under Hypoxia
por: Romero-Garcia, Susana, et al.
Publicado: (2019)

Effects of Oncostatin M on Invasion of Primary Trophoblasts under Normoxia and Hypoxia Conditions
por: Wie, Jeong ha, et al.
Publicado: (2018)

Roles for Plant Mitochondrial Alternative Oxidase Under Normoxia, Hypoxia, and Reoxygenation Conditions
por: Jayawardhane, Jayamini, et al.
Publicado: (2020)

Lipid droplets: a classic organelle with new outfits
por: Fujimoto, Toyoshi, et al.
Publicado: (2008)

Substrate oxidation and the influence of breakfast in normobaric hypoxia and normoxia
por: Griffiths, Alex, et al.
Publicado: (2019)

Gliflozins, Erythropoietin, and Erythrocytosis: Is It Renal Normoxia- or Hypoxia-Driven?
por: Heyman, Samuel N., et al.
Publicado: (2023)

Effect of electric stimulation on human chondrocytes and mesenchymal stem cells under normoxia and hypoxia
por: Hiemer, Bettina, et al.
Publicado: (2018)

Metabolic Interplay between Tumour Cells and Cancer-Associated Fibroblasts (CAFs) under Hypoxia versus Normoxia
por: Wanandi, Septelia Inawati, et al.
Publicado: (2018)

Lipid droplets as ubiquitous fat storage organelles in C. elegans
por: Zhang, Shaobing O, et al.
Publicado: (2010)

Minimal Influence of Hypobaria on Heart Rate Variability in Hypoxia and Normoxia
por: Aebi, Mathias Roland, et al.
Publicado: (2020)

Short-Term Repeated Wingate Training in Hypoxia and Normoxia in Sprinters
por: Takei, Naoya, et al.
Publicado: (2020)

Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia
por: Skaraitė, Ieva, et al.
Publicado: (2023)

Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2
por: al Taleb, Zukaa, et al.
Publicado: (2016)

Markers of physiological stress during exercise under conditions of normoxia, normobaric hypoxia, hypobaric hypoxia, and genuine high altitude
por: Woods, David Richard, et al.
Publicado: (2017)

HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells
por: Koizume, Shiro, et al.
Publicado: (2012)

Cancer cell‐derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin
por: Koizume, Shiro, et al.
Publicado: (2023)

The Impacts of Different Types of Radiation on the CRT and PDL1 Expression in Tumor Cells Under Normoxia and Hypoxia
por: Huang, Yangle, et al.
Publicado: (2020)

Cytosolic lipid droplets as engineered organelles for production and accumulation of terpenoid biomaterials in leaves
por: Sadre, Radin, et al.
Publicado: (2019)

Lipid droplets are central organelles for meiosis II progression during yeast sporulation
por: Hsu, Tzu-Han, et al.
Publicado: (2017)

Validating an artificial organelle: Studies of lipid droplet-specific proteins on adiposome platform
por: Ma, Xuejing, et al.
Publicado: (2021)

Touch and Go: Membrane Contact Sites Between Lipid Droplets and Other Organelles
por: Liao, Pin-Chao, et al.
Publicado: (2022)

Lipid droplets as multifunctional organelles related to the mechanism of evasion during mycobacterial infection
por: de Almeida, Patrícia Elaine, et al.
Publicado: (2023)

Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile
por: Dubbelboer, Ilse R., et al.
Publicado: (2019)

Determinants of curvature constant (W’) of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis
por: Deb, Sanjoy K., et al.
Publicado: (2017)

Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia
por: Zhao, Ashley G., et al.
Publicado: (2020)

Metabolomic Analysis of Small Extracellular Vesicles Derived from Pancreatic Cancer Cells Cultured under Normoxia and Hypoxia
por: Hayasaka, Ryosuke, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tr4abaot1u6l3h125vcdre9b4n