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Cancer-Associated Fibroblasts Modify the Response of Prostate Cancer Cells to Androgen and Anti-Androgens in Three-Dimensional Spheroid Culture

Androgen receptor (AR) targeting remains the gold standard treatment for advanced prostate cancer (PCa); however, treatment resistance remains a major clinical problem. To study the therapeutic effects of clinically used anti-androgens we characterized herein a tissue-mimetic three-dimensional (3D)...

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Detalles Bibliográficos
Autores principales:	Eder, Theresa, Weber, Anja, Neuwirt, Hannes, Grünbacher, Georg, Ploner, Christian, Klocker, Helmut, Sampson, Natalie, Eder, Iris E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037737/ https://www.ncbi.nlm.nih.gov/pubmed/27598125 http://dx.doi.org/10.3390/ijms17091458

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