Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer

Aberrant Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling is crucial to the development of gastric cancer. In this study, we examined the role of STAT3 in the expression and methylation of its targets in gastric cancer patients. Results from RNA sequencing identif...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Shyong, Wei, Kuo-Liang, Chou, Jian-Liang, Lu, Chung-Kuang, Hsieh, Ching-Chuan, Lin, Jora M. J., Deng, Yi-Fang, Hsu, Wan-Ting, Wang, Hui-Min David, Leung, Chung-Hang, Ma, Dik-Lung, Li, Chin, Chan, Michael W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037745/
https://www.ncbi.nlm.nih.gov/pubmed/27598141
http://dx.doi.org/10.3390/ijms17091467

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