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T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure

Alterations of the β-adrenergic signalling, structural remodelling, and electrical failure of T-tubules are hallmarks of heart failure (HF). Here, we assess the effect of β-adrenoceptor activation on local Ca(2+) release in electrically coupled and uncoupled T-tubules in ventricular myocytes from HF...

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Detalles Bibliográficos
Autores principales:	Crocini, Claudia, Coppini, Raffaele, Ferrantini, Cecilia, Yan, Ping, Loew, Leslie M., Poggesi, Corrado, Cerbai, Elisabetta, Pavone, Francesco S., Sacconi, Leonardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037749/ https://www.ncbi.nlm.nih.gov/pubmed/27598150 http://dx.doi.org/10.3390/ijms17091471

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